What is LDN (low dose naltrexone)?

Naltrexone is a synthetic drug that blocks opiate receptors in the                                                                                                    central nervous system, which are responsible for the pillsensation of pleasure derived from narcotics.  Naltrexone is typically used for heroin addiction and is FDA approved at doses of 50mg. It is also used in alcohol and drug addiction.

In recent years, lower doses of naltrexone have been used to treat autoimmune conditions such as MS (multiple sclerosis), rheumatoid arthritis, ulcerative colitis and crohn’s disease. The lower dosing of naltrexone is commonly referred to as LDN (low dose naltrexone). The typical dose ranges from 3.5mg to 4mg and is recommended to be taken at bedtime. Low dose naltrexone is inexpensive and well-tolerated.

LDN was first used by a physician in 1985 who found that it boosted the immune system in AIDS patients. It is thought that by briefly blocking opioid receptors, LDN causes an increase in endorphins and enkephalins (our body’s natural pain killers). These natural opioids are believed to influence our immune system as we have opioid receptors on immune cells. In particular, blocking the opioid receptors at night is thought to cause a longer up regulation hence LDN is recommended to be taken at night.

At Hermann Wellness we offer Holistic Primary Care to our patients including Low Dose Naltrexone. Our offices are located in Tampa and St. Petersburg. Please call the office at 813-902-9559 for more information or to schedule an appointment.